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Table 2 DMPs by cluster membership

From: MMDiff: quantitative testing for shape changes in ChIP-Seq data sets

Cluster 1 2 3 4 5 6 7 8 9 10
N P 362 275 264 352 363 250 84 176 128 232
N Δ 9 2 7 18 24 14 4 4 12 40
p-value ooo ooo ooo ooo ooo ooo   ooo   
Pol II log2 FC 0.04 0.03 -0.03 -0.07 -0.01 -0.05 -0.19 -0.08 -0.22 -0.13
Cluster 11 12 13 14 15 16 17 18   
N P 226 291 228 209 241 167 145 155   
N Δ 24 67 23 78 54 61 28 70   
p-value   ***   *** *** ***   ***   
Pol II log2 FC -0.13 -0.16 -0.11 -0.23 -0.18 -0.23 -0.23 -0.30   
  1. N P : number of promoters associated with the given cluster in WT, N Δ : number of DMPs called by MMDiff, p-values: significance of enrichment/depletion with DMPs by cluster. (***,ooo corresponds to p-values 0.001, where two-sided binomial tests are computed for each cluster. ooo Clusters contain fewer, *** clusters contain more DMPs than expected by chance. Pol II log2 FC: log2 fold change in Pol II binding averaged over all promoters per cluster.)