Table 2 Selected pathways from the first 40 iterations of IFR on the influenza data
From: Iterative feature removal yields highly discriminative pathways
Pathway | Acc | Genes |
|---|---|---|
Interferon Stimulated Genes | 87.7 | AIM2 (4), DDX60 (3), GBP1 (1), HERC5 (8), HERC6 (17), IFI27 (2), IFI30 (21), IFI35 (18), IFI44 (1), IFI44L (2), IFI6 (5), IFIH1 (16), IFIT1 (2), IFIT2 (25), IFIT3 (4), IFIT5 (10), IFITM1 (2), IFITM2 (30), IFITM3 (6), IL15 (17), IL15RA (27), IRF7 (13), IRF9 (12), ISG15 (3), ISG20 (34), MX1 (12), OAS1 (1), OAS2 (10), OAS3 (8), OASL (9), PSME1 (5), PSME2 (3), RSAD2 (3), STAT1 (7), STAT2 (27), STAT5B (30), TRIM22 (5), XAF1 (9) |
Antigen Recognition Genes | 93.0 | CD1C (17), HLA-B (27), HLA-DOB (6), HLA-DPA1 (32), HLA-DQA1 (3), HLA-DQB1 (6), HLA-E (26), MICA (22), TAP1 (7), TAP2 (30) |
TNF Super Family | 89.5 | TNF (28), TNFAIP1 (11), TNFAIP3 (29), TNFAIP6 (22), TNFRSF10B (5), TNFRSF14 (31), TNFRSF4 (11), TNFSF10 (11) |
IL-1 Beta Receptor Family | 86.0 | IL1B (14), IL1F5 (12), IL1R1 (10), IL1RAP (6), IL1RL2 (15), IL33 (24) |
B Cell Maturation and Activation | 91.2 | CD19 (36), CD200 (4), CD22 (10), CD24 (7), CD38 (31), CD40 (23), CD72 (28), CD79A (12), CD86 (16), CD9 (7), IGHD (12), IGHM (5), IGHV3-23 (15) |
Cell Cycle Related | 89.5 | CDC20 (13), CDC45L (8), CDCA3 (14), CDCA8 (7), CDK5 (1), CDK5R2 (6), CDKAL1 (5), CDKL5 (27), CDKN1C (13) |
Programmed Cell Death | 84.2 | CASP10 (33), CASP4 (29), CASP5 (24), CASP7 (6), PCDHA3 (14), PCDHGA11 (5), PDCD1LG2 (2), PDCD4 (14) |
Chemokines | 87.7 | CCL11 (19), CCL5 (36), CCR1 (10), CCR10 (4), CCR3 (29), CCR6 (27), CCRL2 (6), CX3CR1 (35), CXCL10 (30), CXCL11 (29), CXCL6 (15), CXCR5 (37), DARC (39) |
Cell Adhesion Molecules | 87.7 | ICAM3 (3), ICAM4 (15), ICAM5 (29), MADCAM1 (25) |
Cytokine-Cytokine Receptor Signaling | 82.5 | IL16 (10), IL17RC (26), IL18RAP (1), IL22 (11), IL9 (31), SOCS1 (33), SOCS3 (29), SOCS6 (9) |
Complement Pathway | 91.2 | C1QA (2), C1QB (3), C2 (19), C3AR1 (26), CR2 (12) |
Other Immune Response | 93.0 | CD8A (22), FCER1G (7), FCER2 (28), FCRL2 (14), KIR2DL3 (32), LY6E (1), LY9 (8), MARCO (26), TLR5 (8) |