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Table 2 Selected pathways from the first 40 iterations of IFR on the influenza data

From: Iterative feature removal yields highly discriminative pathways

Pathway Acc Genes
Interferon Stimulated Genes 87.7 AIM2 (4), DDX60 (3), GBP1 (1), HERC5 (8), HERC6 (17), IFI27 (2), IFI30 (21), IFI35 (18), IFI44 (1), IFI44L (2), IFI6 (5), IFIH1 (16), IFIT1 (2), IFIT2 (25), IFIT3 (4), IFIT5 (10), IFITM1 (2), IFITM2 (30), IFITM3 (6), IL15 (17), IL15RA (27), IRF7 (13), IRF9 (12), ISG15 (3), ISG20 (34), MX1 (12), OAS1 (1), OAS2 (10), OAS3 (8), OASL (9), PSME1 (5), PSME2 (3), RSAD2 (3), STAT1 (7), STAT2 (27), STAT5B (30), TRIM22 (5), XAF1 (9)
Antigen Recognition Genes 93.0 CD1C (17), HLA-B (27), HLA-DOB (6), HLA-DPA1 (32), HLA-DQA1 (3), HLA-DQB1 (6), HLA-E (26), MICA (22), TAP1 (7), TAP2 (30)
TNF Super Family 89.5 TNF (28), TNFAIP1 (11), TNFAIP3 (29), TNFAIP6 (22), TNFRSF10B (5), TNFRSF14 (31), TNFRSF4 (11), TNFSF10 (11)
IL-1 Beta Receptor Family 86.0 IL1B (14), IL1F5 (12), IL1R1 (10), IL1RAP (6), IL1RL2 (15), IL33 (24)
B Cell Maturation and Activation 91.2 CD19 (36), CD200 (4), CD22 (10), CD24 (7), CD38 (31), CD40 (23), CD72 (28), CD79A (12), CD86 (16), CD9 (7), IGHD (12), IGHM (5), IGHV3-23 (15)
Cell Cycle Related 89.5 CDC20 (13), CDC45L (8), CDCA3 (14), CDCA8 (7), CDK5 (1), CDK5R2 (6), CDKAL1 (5), CDKL5 (27), CDKN1C (13)
Programmed Cell Death 84.2 CASP10 (33), CASP4 (29), CASP5 (24), CASP7 (6), PCDHA3 (14), PCDHGA11 (5), PDCD1LG2 (2), PDCD4 (14)
Chemokines 87.7 CCL11 (19), CCL5 (36), CCR1 (10), CCR10 (4), CCR3 (29), CCR6 (27), CCRL2 (6), CX3CR1 (35), CXCL10 (30), CXCL11 (29), CXCL6 (15), CXCR5 (37), DARC (39)
Cell Adhesion Molecules 87.7 ICAM3 (3), ICAM4 (15), ICAM5 (29), MADCAM1 (25)
Cytokine-Cytokine Receptor Signaling 82.5 IL16 (10), IL17RC (26), IL18RAP (1), IL22 (11), IL9 (31), SOCS1 (33), SOCS3 (29), SOCS6 (9)
Complement Pathway 91.2 C1QA (2), C1QB (3), C2 (19), C3AR1 (26), CR2 (12)
Other Immune Response 93.0 CD8A (22), FCER1G (7), FCER2 (28), FCRL2 (14), KIR2DL3 (32), LY6E (1), LY9 (8), MARCO (26), TLR5 (8)
  1. Selected pathways relating to genes taken from the first 40 iterations of IFR on the influenza data. The iteration that the genes were discovered is in parentheses. Acc indicates the classification accuracy (percent) using only the genes in each list.
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