Figure 4

Methanol up-regulation and down-regulation of H. polymorpha genes distributed to various KEGG categories. Metabolism: 1 - Carbohydrate metabolism, 2 - Energy metabolism, 3 - Lipid metabolism, 4 - Nucleotide metabolism, 5 -Amino acid metabolism, 6 - Glycan biosynthesis and metabolism, 7 - Metabolism of cofactors and vitamins, 8 - Biosynthesis of other secondary metabolites, 9 - Xenobiotic biodegradation and metabolism. Genetic Information Processing: 10 - Transcription, 11 - Translation, 12 - Folding, sorting and degradation, 13 - Replication and repair. Environmental Information Processing: 14 - Signal transduction. Cellular Processes: 15 - Transport and catabolism, 16 - Cell growth and death. Fractions of methanol-induced genes are shown in green, glucose-induced genes in red, and genes without significant changes in expression in yellow.