Table 1 Categories that were significantly enriched (p-value below 0.01) based on the physiological function of the genes whose elimination increases the susceptibility to acetic acid

Biological Process

 Mitochondrial translation [GO:0032543]

1.83E-09

23

88

 Translation [GO:0006412]

4.51E-06

41

318

 ATP hydrolysis coupled proton transport [GO:0015991]

3.76E-05

7

17

 Regulation of SNARE complex assembly [GO:0035542]

1.97E-04

4

6

 Ion transport [GO:0006811]

2.75E-04

17

107

 Protein N-linked glycosylation [GO:0006487]

7.11E-04

8

33

 Proton transport [GO:0015992]

7.28E-04

9

41

 Protein lipoylation [GO:0009249]

9.01E-04

3

4

 Golgi to endosome transport [GO:0006895]

1.12E-03

5

14

 Protein complex assembly [GO:0.001261]

1.26E-03

7

28

 Proteolysis [GO:0006508]

1.79E-03

12

74

 Mitochondrial translational initiation [GO:0070124]

2.15E-03

3

5

 Positive regulation of gluconeogenesis [GO:0045722]

2.15E-03

3

5

 Group I intron splicing [GO:0000372]

2.26E-03

4

10

 Deoxyribonucleotide biosynthetic process [GO:0009263]

4.10E-03

3

6

 Vacuolar acidification [GO:0007035]

4.33E-03

6

26

 Positive regulation of mitochondrial translation [GO:0070131]

4.82E-03

4

12

 tRNA aminoacylation for protein translation [GO:0006418]

4.92E-03

7

35

 Regulation of vacuole fusion. non-autophagic [GO:0032889]

6.62E-03

4

13

 Positive regulation of transcription from RNA polymerase II promoter [GO:0045944]

8.37E-03

13

100

 Mitochondrial respiratory chain complex IV assembly [GO:0033617]

8.83E-03

4

14

Cellular Component

 Mitochondrion [GO:0005739]

2.42E-11

118

1072

 Mitochondrial large ribosomal subunit [GO:0005762]

1.79E-08

15

43

 Mitochondrial ribosome [GO:0005761]

3.90E-06

6

9

 alpha-1.6-mannosyltransferase complex [GO:0000136]

5.07E-06

5

6

 CORVET complex [GO:0033263]

5.07E-06

5

6

 Mitochondrial inner membrane [GO:0005743]

1.31E-04

27

204

 Ribosome [GO:0005840]

1.64E-04

36

310

 HOPS complex [GO:0030897]

1.97E-04

4

6

 Proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178]

4.37E-04

4

7

 Ribonucleoside-diphosphate reductase complex [GO:0005971]

9.01E-04

3

4

 Mitochondrial matrix [GO:0005759]

1.23E-03

16

111

 Large ribosomal subunit [GO:0015934]

2.20E-03

5

16

 Ribonucleoprotein complex [GO:0030529]

2.38E-03

32

307

 Transcriptional repressor complex [GO:0017053]

3.83E-03

2

2

 Mitochondrial proton-transporting ATP synthase, catalytic core [GO:0005754]

3.83E-03

2

2

 SPOTS complex (serine palmitoyltransferase) [GO:0035339]

4.10E-03

3

6

 Extrinsic to mitochondrial inner membrane [GO:0031314]

5.01E-03

5

19