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Figure 5 | BMC Genomics

Figure 5

From: An integrated approach to characterize transcription factor and microRNA regulatory networks involved in Schwann cell response to peripheral nerve injury

Figure 5

The SC injury response regulatory network inferred by integrating experimental data and computational prediction. Circles: TFs. Hexagons: miRNAs. Blue nodes: TFs or miRNAs correlated with myelination gene clusters. Red nodes: TFs or miRNAs correlated with proliferation gene clusters. Grey nodes: master TF or miRNA regulators of coexpressed genes. Black edges: regulatory interactions derived from TF ChIP-Seq data. Grey edges: regulatory interactions inferred by computational prediction. Arrowed edges: activation by TFs. T-shaped edges: repression by TFs or miRNAs.

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