Figure 4

Functional description of genes associated with different TSS classes. The proportions of gene sets associated with different classes of TSS (‘tight’, ‘intermediate’ and ‘diffuse’) with general functional gene ontology descriptions. In total, 4637, 4557 and 2197 genes were asociated with ‘tight’, ‘intermediate’ and ‘diffuse’ TSS, respectively. Of these genes, the proportion of each set associated with a given GO term is plotted (note that genes can be associated with more than one GO term). Differences among the frequencies of GO terms reflect their overall frequency distribution across the genome. In addition, the frequencies of some functional descriptions vary among the different TSS classes. For instance, translation and ribosome biogenesis are distinctly skewed towards genes with tight TSS.