Figure 3
From: De novo copy number variations in cloned dogs from the same nuclear donor
Examples of allelic imbalance in clone-3. (A) Upper panel, Log2ratio plot on chromosome X in clone 3. A 5.2-Mb copy number gain region on chromosome X was identified in clone-3 (black arrow). The X-axis represents genomic position (Mb) and the Y-axis represents signal intensity ratio on a log2 scale. Lower panel, B-allele plot of the proximal part of chromosome X (dashed box of upper panel). A heterozygous cluster was detected in chromosome X (black arrow), and this allelic imbalance has the same genomic position as the copy gain region. (B) Upper panel, Log2ratio plot on chromosome 19 in the clone-3. A 338-Kb copy number gain region on chromosome 19 was identified in clone-3 (black arrow). Lower panel, B-allele plot of the dashed box on chromosome 19. A heterozygous cluster was detected on chromosome 19 (black arrow), and this allelic imbalance has same position as the copy gain region.