From: Recombinant structures expand and contract inter and intragenic diversification at the KIR locus
 |  |  | Gene copy determination using peak ratios | ||
---|---|---|---|---|---|
Amplicon a | Exon | Genes amplified b | Gene ratios | SNP ratios c | Observed peak ratios |
2DL2-001 | 5 | 2DL2, 2DL3, 2DS2, 2DP1 (3DL2) | (2DS2+2DL2+2DL3):2DP1 | C:T at 137 | 1:1, 2:1, 3:1, 3:2, or 4:1 |
(2DL2+2DL3):2DP1 | A:C at 206 | 1:1 or 2:1 | |||
(2DL2+2DL3):2DS2 | 206(A):209(T) | 1:1 or 2:1 | |||
2DL3-006 | 7/8 | 2DL3, 2DS3/5 | 2DL3:2DS35 | G:T at 136 | 1:1, 2:1, 1:2 |
2DL5 | 3 | 2DL1/4/5 3DP1 | 2DL5:(2DL4+3DP1) | G:C at 170 | 1 or multiple copies |
2DP1-002 | 3 | 2DP1 | No ratio data | Â | Â |
2DS2-002 | 4 | 2DL1/2/3, 2DS2, 3DP1 | No ratio data | Â | Â |
2DS35-005 | 4 | 2DS1, 2DS3/5, 3DP1, (2DL1) | 2DS1:2DS3 | A:G at 446 | 1:1 or 1:2 |
2DS3:2DS5 | 446(G):447(A) | 1:1, 2:1, 1:2 | |||
3DL1-002 | 4 | 3DL1, 3DS1 | Â | Â | Â |
3DL1-005 | 4 | 3DL1, 3DS1 | 3DL1:3DS1 | T:G at 167 | 1:1 |
KIR-2DL2-N1 | 4 | 2DL2/3, 2DS2 2DP1 | 2DS2:2DP1 | 213(A):217(C) | 1:1 or 1:2 |
KIR-2DS2-N1 | 5 | 2DL2/3 2DP1 2DS2 | No ratio data | Â | Â |
2DS1-4-002 | 4 | 2DS1, 2DL1, 2DS4 (2DS35) | 2DS1:2DL1:2DS4 | A:C:T at 257 | 1:1:1, 1:2:1, 0:1:1, 0:2:1, or 0:1:2 |
2DS1-004 | 4 | 2DS1, 2DL1, (2DS4) | No ratio data | Â | Â |
3DL1-3DS1-01 | 4 | 3DL1, 3DS1, 3DL2 | (3DL1+3DS1):3DL2 | Multiple SNPs | 1:1, 0:2, 1:2 or 3:2 |
3DL1-3DS1-05 | 4 | 3DL1, 3DS1, 3DL2 | (3DL1+3DS1):3DL2 | Multiple SNPs | 1:1, 0:2, 1:2 or 3:2 |