Table 3 Summary of KIR haplotype motif frequencies

Centromere

Number

Freq (%)

cA01

6036

66.93

cB01

1042

11.55

cB02

1340

14.86

Telomere

tA01

6728

74.61

tB01

1770

19.63

Submotif patterns

Associated region

Number

Freq (%)

cB03-2DL5-2DS35 insertion

cA01

22

0.24

del3–2DS2-deletion

cB01, cB02

24

0.27

del4-2DL2-deletion

cB01

2

0.02

del9–2DL5-2DS35-2DP1 deletion

cB01

2

0.02

del10–2DL2-2DL5-2DS35 deletion

cB01

17

0.19

hybd1–3DL1-3DL2 hybrid/2DS4 deletion

tA01

35

0.39

del5–3DP1-2DL4-3DL1 deletion

(cA01/cB01)|tA01

10

0.11

del6–3DP1-2DL4-3DS1 deletion

(cA01/cB02)|tB01

214

2.37

del7 or del8–2DP1(partial)-3DP1-2DL4-3DS1-2DL5-2DS35-2DS1(partial) deletion

(cA01/cB01)|tB01

55

0.61

ins3–3DP1-2DL4-3DL1 insertion

(cA01/cB01/cB02)|tA01 (cA01/cB01)|tB01

14

0.16

ins4–3DP1-2DL4-3DS1 insertion

(cA01/cB01/cB02)|tA01 (cA01/cB01)|tB01

91

1.01

ins5–3DP1-2DL4-3DS1-2DL5-2DS35-2DS1(partial) insertion and additional recombination with 2DP1

(cA01/cB01/cB02/cB03)|tA01 cB01|tB01

95

1.05

Combined submotifs

cB01|tA01 cB02|tB01

14

0.16

Singlets

10

0.11