Figure 3From: Epigenetic regulation of MDR1 gene through post-translational histone modifications in prostate cancerCharacterization of the methylation status of individual CpG dinucleotides by bisulfite sequencing. The upper panel of the diagram represents the region of the gene under analysis, bisulfite sequence (BSP) and quantitative MSP (qMSP) primers (black arrows) and CpG dinucleotides density (vertical bars). The lower panel shows the status of methylation for each CpG dinucleotide for three different PCa cell lines (LNCaP, DU145 and PC3) exposed to epigenetic drugs. White circle – unmethylated CpG (0–0.20); grey circle – partially methylated CpG (0.21 - 0.80); black circle – fully methylated CpG (0.81 - 1.0).Back to article page