Figure 3From: A unique in vivo experimental approach reveals metabolic adaptation of the probiotic Propionibacterium freudenreichii to the colon environmentOverview of Propionibacterium freudenreichii metabolism of in the colonic environment compared to spent medium. Differential comparisons between groups were performed gene by gene using a modified t-test. Genes were declared as differentially expressed with P value ≤ 0.001 and |fold change| > 2. In blue, genes repressed in the colonic environment: glycolysis, tricarboxylic acid cycle (TCA), Wood-Werkman cycle, oxidative phosphorylation. In red, gene induced or stably expressed in the colonic environment compared to spent medium: pentose phosphate, gluconate, inositol, propanediol, uracil and branched-chain amino-acid degradation.Back to article page