Figure 2

Illustration of copy number alterations and gene expression value associations in hESC and hiPSC samples. The figures depict associations detected in human embryonic (hESC) and induced pluripotent stem cell (hiPSC) data and associations with colored based on the correlation value. The file has 45,791 edges and the upload and plotting took 5 seconds. A) POMO illustration of the best 2000 correlations shows 2000 edges and with heatmap rings hiPSC/hESC expressing high/low gene expression with CNV gain and loss. Green edges indicate positive correlations while pink indicates negative. B) The result is further filtered using set membership check on the gene list taken from KEGG WNT pathway and the edge weight abs (correlation) > = 0.92, yielding 160 edges. C) The result in sub-Figure B is illustrated with the Cytoscape Web radial layout.