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Table 1 JunD levels and macrophage oxidative burst in rat strains used for the combined ChIP-Seq and transcriptome approach

From: Combined ChIP-Seq and transcriptome analysis identifies AP-1/JunD as a primary regulator of oxidative stress and IL-1β synthesis in macrophages

Strain

JunD levels in macrophages*

Macrophage activation**

WKY

+++

+++

WKY.LCrgn2

+

+

Lewis

+

+

  1. * Jund expression levels and JunD/AP-1 protein binding measured by qRT-PCR and TransAm assay [12].
  2. ** Macrophage activation assessed by Fc receptor mediated oxidative burst [12].