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Table 4 Transcription of core FeHm-responsive genes in the NTHi isolates 86-028NP and HI1722

From: Comparison of transcription of the Haemophilus influenzae iron/heme modulon genes in vitro and in vivo in the chinchilla middle ear

  

Fold Changeb

  

86-028NP

HI1722

 Locusa

 Gene

In vitro

In vivo c

in vitro

in vivo d

HI0035

 

2.25

15.53

1.07

29.37

HI0075

nrdD

2.4

3.81

5.28

21.31

HI0095

 

9.69

7.11

29.61

22.01

HI0097

hitA

19.92

2.38

66.15

34.66

HI0113

hemR

1.68

2.47

3.02

5.82

HI0153

dcuB

1.96

7.17

1.39

5.57

HI0253

exbB

3.11

-2.44

9.02

37.74

HI0263

hxuB

5.97

5.95

11.91

14.19

HI0362

yfeA

3.14

2.17

19.93

81.46

HI0534

aspA

5.19

6.74

-1.06

36.7

HI0584

 

1.75

2.52

1.03

10.05

HI0661

hgpB

11.36

3.01

25.6

129.37

HI0691

glpK

1.39

1.22

-1.11

4.26

HI0809

pckA

2.48

1.3

1.51

29.87

HI0994

tbp1

8.73

3.65

15.66

28.3

HI0997m

ompU1

12.68

42.36

7.77

30.71

HI1210

mdh

2.11

2.58

1.21

3.5

HI1356

malQ

2.36

10.27

-1.92

10.86

HI1369

 

8.94

30.26

5.15

30.63

HI1427

 

3.63

8.8

3.33

7.42

HI0007

fdnH

-2.3

1.15

-3.84

1.81

HI0185

adhC

-4.48

-1.42

-5.35

-1.42

HI0343

napD

-1.38

1.56

1.00

12.4

HI0980

fis

-1.05

1.26

-1.18

2.36

HI1069

nrfA

-5.08

2.28

-5.06

9.69

HI1078

tcyC

-1.92

2.58

-1.01

3.79

HI1094

ccmF

-1.51

9.74

-2.01

4.68

HI1384

ftnA

-4.27

-7.88

-6.89

-5.41

  1. aGene locus in Rd KW20.
  2. bFold difference in gene expression levels in theFeHm-deplete in vitro sample when normalized to replete condition. Numbers in bold are data points that differ in fold change from that predicted by the core FeHm regulon.
  3. cGeometric mean of 18 samples, normalized to heme-replete in vitro sample.
  4. dGeometric mean of 6 samples, normalized to heme-replete in vitro sample.
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BMC Genomics

ISSN: 1471-2164

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