Figure 4

Fluorescence in situ hybridization (FISH) performed using duplex-probes (×1000). a. Hoechst33342 (Blue). b. hsa-mir-622 family (Green). c. hsa-mir-1233 family (Red). d. The merged signals indicate two probes hybridize to genomic sequences close to each other, which is in agreement with the computational prediction results.