BMC Genomics

Table 1 Comparison of ${\hat{f}}_{em}$ and ${\hat{f}}_{avg}$ in terms of mean squared error

From: A unified approach for allele frequency estimation, SNP detection and association studies based on pooled sequencing data using EM algorithms

	α= 0.05%		α= 0.1%		α= 0.5%		α= 1%
	MSE	Cg	MSE	Cg	MSE	Cg	MSE	Cg
f = 0.1%	0	0	0	0	0	0	0	0
f = 0.5%	9	5	4	3	0	0	0	0
f = 1%	13	10	9	7	0	0	0	0
f = 5%	17	16	17	16	12	12	7	7

Number of scenarios where MSE_em > MSE_avg or Cg_em > Cg_avg out of 18 total scenarios for each cell.

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ISSN: 1471-2164

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