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Table 1 Different types of yeast fitness profiles deposited in FitRankDB.

From: FitSearch: a robust way to interpret a yeast fitness profile in terms of drug's mode-of-action

Type of treatment

Type of genome-wide deletion library

Type of fitness profile

Profile #

Chemical effect1

Homozygous deletion strains3

Chemical-genetic (Hom)

918

Chemical effect

Heterozygous deletion strains3

Chemical-genetic (Het)

1,530

Genetic effect2

Homozygous deletion strains

Genetic-genetic (Hom)

12,419

  1. See the details at http://pombe.kaist.ac.kr/fitsearch/statistics/
  2. 1 For example, drug, bioactive compounds or natural crude extracts
  3. 2 For example, knock-out, over-expression or mutation of a gene
  4. 3 Homozygous (or haploid) and heterozygous (or diploid) deletion collections of S. cerevisiae and S. pombe are commercially available at Open Biosystems (http://www.openbiosystems.com) and Bioneer (http://pombe.bioneer.co.kr), respectively.
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BMC Genomics

ISSN: 1471-2164

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