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Table 2 Results of running Velvet and our method on E.coli-based genomes.

From: Genome reassembly with high-throughput sequencing data

  Velvet Our method
Donor genome # Contigs N50 Max contig # Contigs N50 Max contig Accuracy
E. Coli O157, 5 Kb 1034 25477 158013 422 56750 274293 99.5%
E. Coli O157, 25 Kb 870 71194 286061 727 96535 285958 99.6%
E. Coli K12 166 125649 327149 33 429486 734812 97.0%
  1. In the first three cases, simulated donor genomes are derived from the O157 reference by applying a series of mutations (insertions, deletions, and SNVs). In the final case, the K12 E. coli strain is used as a donor and compared against the O157 reference.