Figure 3
From: Pathway analysis of genome-wide data improves warfarin dose prediction
LD-weighted A#m scores are calculated by taking the sum of all minor alleles multiplied by their respective weights. In this case, the SNPs in the black box are in tight LD, while the SNPs in the green box are in moderate LD. With SNP weighting, rather than pruning the SNPs in LD, SNPs are weighted based on the contribution of independent information to the A#m score.