Comparison between Meta-SNP, CONDEL and PhD-SNP. (A) Performances of CONDEL, PhD-SNP and Meta-SNP on the NSV-2012 dataset. (B) Meta-SNP accuracy on NSV-2012 dataset and its three subsets. (C) Accuracy of Meta-SNP in terms of TPR and TNR improves as a function of increasing. Note that there are only 25 disease causing variants at RI = 9, resulting in an artifact of the curve - an unexpected drop in accuracy, RI. TPR, TNR and RI are defined in Methods. DB is the fraction of the NSV-2012 dataset with an RI higher or equal than a given threshold.