Skip to main content

Table 1 Component method performance

From: Collective judgment predicts disease-associated single nucleotide variants

Method Q2 PPV TPR NPV TNR MCC AUC %DB
PANTHER 0.74 0.79 0.73 0.69 0.74 0.48 0.82 74
PhD-SNP 0.76 0.78 0.74 0.75 0.78 0.53 0.84 100
SIFT 0.70 0.74 0.64 0.68 0.76 0.41 0.73 92
SNAP 0.64 0.59 0.90 0.79 0.38 0.33 0.79 100
  1. Q2=Overall accuracy, PPV and NPV=Positive and Negative Predicted Values, TPR and TNR=True Positive and Negative Rates. MCC=Mathew's correlation, AUC=area under the (ROC) curve, %DB is the fraction of the SV-2009 dataset for which a prediction is returned.