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Table 3 Classifier performance. Classifier performance on the benchmark test set. Area under the curve (AUC) statistics for Receiver Operating Characteristics and Precision-Recall curves are shown

From: Identifying Mendelian disease genes with the Variant Effect Scoring Tool

  Performance on benchmark Performance on benchmark (subset scored by all methods)
Method ROC AUC PR AUC ROC AUC PR AUC
VEST 0.912 0.919 0.917 0.884
PolyPhen2 0.857 0.840 0.854 0.762
SIFT4.0 0.835 0.715 0.838 0.724