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Table 2 Breakdown of the number of mutations in SAAPdb and their mapping to structure.

From: The SAAP pipeline and database: tools to analyze the impact and predict the pathogenicity of mutations

Number of Mutations PDs SNPs
Mapped to UniProtKB/SwissProt 13,059 48,452
Mapped to PDB 6,527 17,915
Mapped to multiple PDBs 202,566 33,369
Mapped to multiple Chains 405,497 45,699
  1. In some cases, several hundred structures are available (e.g. haemoglobin, carbonic anhydrase, prthrombin, transthyretin, insulin, CDK2, lysozyme) and, on average there are approximately two copies of each chain in each PDB file.