Figure 3

Comparing orthologous genes and common protein domains between yeast and human. Yeast and human protein mutations that can be related to mutations in other organisms through either orthologous genes from Homologene or through common protein domains. For both yeast (A) and human (B) mutations, each portion of the graph represents the mutations that could not be related to the other organism (orange), the mutations that could be related only through Homologene (yellow), the mutations that could be related using only common protein domains (blue), and the mutations that could be related using either method (purple).