A protein domain-centric approach for the comparative analysis of human and yeast phenotypically relevant mutations

Table 3 Shared and unique domain hotspots between the yeast and human datasets.

	Domain Hotspot Count (1.6)	Domain Hotspot count (1.3)	Domain Hotspot Count (1.0)
Position-based domain hotspots only found in yeast	100	113	134
Position-based domain hotspots only found in human	718	883	1,084
Feature-based domain hotspots only found in yeast	688	751	845
Feature-based domain hotspots only found in human	3,094	3,328	3,791
Position-based domain hotspots shared between yeast and human	1	1	1
Feature-based domain hotspots shared between yeast and human	103	118	177

Position-based and feature-based domain hotspots for yeast and human sharing a common domain position at 1.6, 1.3, and 1.0 DS-Score thresholds.

ISSN: 1471-2164