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Table 4 Multi-species domain hotspots

From: A protein domain-centric approach for the comparative analysis of human and yeast phenotypically relevant mutations

 

Domain Hotspot Count (1.6)

Domain Hotspot count (1.3)

Domain Hotspot Count (1.0)

Total multi-species position-based domain hotspots

861

1,078

1,331

Total multi-species feature-based domain hotspots

4,243

4,809

5,439

Multi-species position-based domain hotspots not identified in yeast or human

143

187

238

Multi-species feature-based domain hotspots not identified in yeast or human

1,243

1,533

1,672

  1. Position-based and feature-based domain hotspots identified by applying the DS-Score to a combined set of yeast and human mutations. This table shows the number of multi-species domain hotspots we can identify at each threshold, as well as the number of domain hotspots that were not previously identified when analyzing mutations from only yeast or only human.