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Table 3 Performance of the different methods on the SAP-3D dataset

From: WS-SNPs&GO: a web server for predicting the deleterious effect of human protein variants using functional annotation

Method

Otot

P[D]

S[D]

P[N]

S[N]

MCC

AUC

PhD-SNP

0.79

0.83

0.74

0.76

0.84

0.58

0.87

S3D-PROF

0.81

0.80

0.84

0.83

0.78

0.63

0.88

SNPs&GO

0.81

0.80

0.83

0.82

0.78

0.61

0.89

SNPs&GO3d

0.84

0.82

0.86

0.85

0.81

0.68

0.91

  1. D=disease related, N=neutral. For index definition see "Measures of performance".
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BMC Genomics

ISSN: 1471-2164

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