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Table 2 ATC second sublevel categories significantly enriched in illicit drugs compared to other drugsa

From: Exploring drug-target interaction networks of illicit drugs

ATC code ATC therapeutic subgroup # of illicit drugs (%b) # of other drugs (%c) p-valued
N05 Psycholeptics 24 (48.0) 3 (0.5) 1.2 × 10-26
N01 Anesthetics 5 (10.0) 0 (0) 2.3 × 10-6
A08 Antiobesity preparations, excluding diet products 4 (8.0) 1 (0.2) 1.5 × 10-4
N02 Analgesics 6 (12.0) 11 (1.9) 1.0 × 10-3
A14 Anabolic agents for systemic use 2 (4.0) 0 (0) 5.9 × 10-3
N06 Psychoanaleptics 3 (6.0) 4 (0.7) 0.012
R05 Cough and cold preparations 2 (4.0) 1 (0.2) 0.017
  1. aThe other drugs represent the drugs in the full drug-target network excluding illicit drugs and illicit-related drugs. Among those other drugs, 594 have ATC second sublevel classifications.
  2. bThe proportion of illicit drugs belong to a given ATC category among the 50 illicit drugs with ATC second sublevel classifications.
  3. cThe proportion of other drugs belong to a given ATC category among the 594 other drugs with ATC second sublevel classifications.
  4. dp-value was calculated by Fisher's exact test.