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Table 2 Genetic expression model with negative autoregulation

From: How reliable is the linear noise approximation of gene regulatory networks?

parameter

Value

parameter

value

k 0

50 Ω ̃ (nM)

k s

50h-1

k dM

5h-1

k dp

0.5h-1

k 1

0.5 · (nMh)-1

k -1

1h-1

k 2

0.5 · (nMh)-1

k -2

k -1

k 3

0.5 Ω ̃

k -3

450h-1

k 4

50 · k3

k -4

k -3

k 5

0.25 · (nMh)-1

k -5

0.5h-1

k 6

5 · (nMh)-1

k -6

5h-1

k 6 ′

10h-1

k 5 ′

0.5h-1

Ω ̃

450 · (nM)-1

  
  1. Kinetic parameters for the model of autoregulated gene model for a volume of 7.5 × 10-13l. Note that here the parameter Ω ̃ is the inverse concentration of a single molecule. The total enzyme concentration of E, K, R is given by 0.5nM while the concentration of D is 5nM.
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BMC Genomics

ISSN: 1471-2164

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