Table 1 Modularity analysis from SHCN
Gene module by MCL algorithm | Functional annotations by DAVID |
|---|---|
DPP4, FCGR3A, PTPRC, IFNAR1, IFNA1, LCK | T cell activation, leukocyte and lymphocyte activation, cell surface receptor linked signal transduction Natural killer cell mediated cytotoxicity |
ATF3, RNF187, MAFB, JUN, ASCC2 | Transcription factor activity, DNA binding, regulation of transcription |
FUT4, ITGB2, TLR4, CD14, PRKCH | Inflammatory response, receptor complex |
VEPH1, BMPR1B, RPS27A | Cell part |
TCERG1, WAS, FYB | Unknown |
TRPC4, TRPC5, ITPR2 | Calcium binding, intrinsic to membrane |
TBC1D8, TRAF4, SORBS2 | Alternative splicing |