Figure 2

Function annotation of human lincRNAs. (a) flowchart of co-expression association annotation. Expression profile across hES and 16 human adult tissues was filtered for low expressed genes. Then, Gini correlations were calculated and neighbors of each lincRNA were selected to do GO enrichment analysis. We got a list of enriched GO slim terms and their corresponding lincRNAs by mapping GO terms to GO slim terms. Finally, we did Fisher's exact test to test whether interested lincRNA sets were enriched in each GO slim terms. Please see details in GO enrichment analysis section in Data Preparation of Methods and Materials. (b) Significantly enriched biological processes of hES lincRNAs, (c) hES biased lincRNAs.