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Figure 3 | BMC Genomics

Figure 3

From: Genome-wide structural modelling of TCR-pMHC interactions

Figure 3

Comparison between the TCR-pMHC and antigen-antibody interfaces. (A) Pearson's correlation coefficient of 20 amino acid preferences within paired interfaces among TCR-peptide, antigen-antibody, and protein-protein interfaces. (B) Hydrogen bonding proportions in contact pairs for three kinds of interfaces. (C) Structure alignment of TCR-pMHC (PDB entry: 1ao7) and antigen-antibody (PDB entry: 1jps) complexes using MultiProt. αβTCR chains (orange) are aligned to heavy and light chains of antibody (light blue) and the RMSD is 1.82 Å.

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