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Figure 1 | BMC Genomics

Figure 1

From: RETRACTED ARTICLE: Coffee component hydroxyl hydroquinone (HHQ) as a putative ligand for PPAR gamma and implications in breast cancer

Figure 1

HHQ docked in the ligand binding domain of PPARγ protein crystal structure for PDB solved in conjunction with Rosiglitazone (PDBID: 2PRG). [A] Represents hydrogen bonds (in black dotted line) observed for Rosiglitazone (in red) with the active site residues in the ligand binding domain of PPARγ (2PRG). [B] Represents hydrogen bonds (in black dotted line) observed for HHQ (in yellow) with the active site residues in the ligand binding domain of 2PRG. [C] Represents superposition of the best conformation of Rosiglitazone (in red) and HHQ (in yellow) in the ligand binding domain of 2PRG.

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