Figure 2

ITGA6 gene silencing in human TEC down-regulates the membrane expression of other integrin α-subunits. Membrane expression of the integrin α-chains CD49b, CD49c and CD49d was evaluated by cytofluorometry and data are expressed as mean fluorescence intensity. The individual bars on the graph represent mean ± standard error (n = 4), and p -values were generated using Student's t-test. *p < 0.05 and **p < 0.01.