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Table 4 The group of antiinflammatory and antitumor genes screened from microarrays

From: Substrate-dependent gene regulation of self-assembled human MSC spheroids on chitosan membranes

Gene symbol

Gene full name

Ratio (MA)

Ratio (qRT-PCR)

IL1A

interleukin 1, alpha

2.12

3.48 ± 1.09*

IL1B

interleukin 1, beta

2.12

-

IL1RN

interleukin 1 receptor antagonist

6.33

5.72 ± 0.88*

IL33

interleukin 33

3.85

-

IRAK2

interleukin-1 receptor-associated kinase 2

2.50

-

IL4I1

interleukin 4 induced gene 1

2.34

-

IL24

interleukin 24

4.77

18.59 ± 10.05*

IL6ST

interleukin 6 signal transducer (gp130, oncostatin M receptor)

4.07

-

LIF

leukemia inhibitory factor

2.02

3.70 ± 1.77*

TNFAIP8L3

tumor necrosis factor, alpha-induced protein 8-like 3

13.87

10.28 ± 2.41*

TNFAIP8

tumor necrosis factor, alpha-induced protein 8

3.89

7.02 ± 1.75*

TNFAIP6

tumor necrosis factor, alpha-induced protein 6

3.31

-

TNFSF13B

tumor necrosis factor (ligand) superfamily, member 13b

2.50

-

TNFSF9

tumor necrosis factor (ligand) superfamily, member 9

2.36

-

TNFRSF11B

tumor necrosis factor receptor superfamily, member 11b

2.23

-

C1QTNF6

C1q and tumor necrosis factor related protein 6

2.43

-

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

4.71

15.09 ± 1.73*

TP53

tumor protein p53

2.11

1.48 ± 0.03*

  1. *P < 0.05 between CS and TCPS groups (n = 5).