QTLs associated with dry matter intake, metabolic mid-test weight, growth and feed efficiency have little overlap across 4 beef cattle studies

Table 5 Large-effect QTL associated with mid-test body weight in 4 different beef populations

BTA_Mb¹	Population²	Start SNP	End SNP	Number of SNPs	Genetic variance (%)	Nominal P-value	Bonferroni corrected P-value	Lead-SNP	sPPI³
1_98	Angus	rs41638981	rs110173036	265	1.94	1.07E⁻⁵	2.88E⁻²	rs135605472	0.55
6_38	Cycle VII	rs29010895	rs81131471	21	3.49	4.78E⁻⁷	1.21E⁻³	rs109294917	0.55
6_39	Cycle VII	rs81139192	rs81129153	25	2.08	7.52E⁻⁶	1.89E⁻²	rs110012183	0.54
7_0	Angus	rs134214229	rs133987755	219	3.99	2.26E⁻⁷	6.08E⁻⁴	rs134458731	0.89
7_23	Angus	rs133100477	rs42926834	261	14.24	8.99E⁻¹¹	2.41E⁻⁷	rs136491020	0.57
7_93	Hereford	rs134145330	rs109802727	183	2.55	2.61E⁻⁶	7.00E⁻³	rs110680622	0.05
14_24	Sim × Ang	rs109637592	rs109636480	192	3.14	8.54E⁻⁷	2.29E⁻³	rs134751608	0.08
18_63	Hereford	rs110348373	rs42522614	225	1.76	1.75E⁻⁵	4.69E⁻²	rs41897307	0.39
20_4	Hereford	rs134565601	rs43094976	299	3.78	3.07E⁻⁷	8.23E⁻⁴	rs133032375	0.08
20_6	Sim × Ang	rs42517095	rs42352270	288	2.58	2.45E⁻⁶	6.56E⁻³	rs133488748	0.07
21_13	Angus	rs109890770	rs137407067	277	1.97	9.92E⁻⁶	2.66E⁻²	rs41592029	0.54

¹Bovine chromosome and n^th 1-Mb window within the same chromosome starting at 0 Mb and based on the UMD3.1 assembly.
²Sim × Ang stands for Simmental × Angus. The Cycle VII population was genotyped with the BovineSNP50 assay while the other populations were genotyped with the BovineSNP50 and BovineHD assays and imputed to the BovineHD content using Beagle 4.0.
³sPPI: posterior probability of inclusion for the given lead-SNP.

ISSN: 1471-2164