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Figure 8 | BMC Genomics

Figure 8

From: Illumina identification of RsrA, a conserved C2H2 transcription factor coordinating the NapA mediated oxidative stress signaling pathway in Aspergillus

Figure 8

Model integrating RsrA into the global ROS-responsive network in A. nidulans. Upon hydrogen peroxide exposure, the bZIP transcription factor NapA gets directly oxidized and thereby activates gene expression of enzymes and components (TrxA, CatB) involved in balancing the redox status of the cells. RsrA acts as a repressor of certain NapA-activated target genes, perhaps in balance with the AnCF complex. How RsrA is activated itself remains unclear.

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