Figure 6
From: Functional chromatin features are associated with structural mutations in cancer
Distribution of functional chromatin state at the breakpoints. A. Histogram of chromatin state (Broad-GM12878) at the breakpoints in the Breast-Stephens SM callset. Teal and white bars indicate observed vs. expected values, respectively. Error bars indicate binomial standard error. B. Zoom-in view of chromatin state histogram for selected states. C and D. Correlations between chromatin state (Broad-H1HESC) for pairs of breakpoints from the same SM in the Breast-Stephens SM callset. The numbers indicate counts of SM events with their breakpoints in the two labeled states. The color scale indicates difference between the observed frequency of SM events and the expectation if breakpoints were independent, presented on a linear scale (eg. observed frequency of 30% vs. expected of 20% maps to 0.10 on the scale). C. Both inter- and intrachromosomal events. D. Interchromosomal events only.