Skip to main content

Table 1 Genes involved in GPI-anchor biosynthesis and their mutant alleles

From: Simulation and estimation of gene number in a biological pathway using almost complete saturation mutagenesis screening of haploid mouse cells

    No. of mutant alleles
Gene Chr CDS length (bp) H129-2 HAP-1 Total
Pigc 1 891 2 2 4
Pigm 1 1269 5 4 9
Pign 1 2793 NA* NA* NA*
Dpm1 2 780 2† 3 5
Dpm2 2 252 0 1 1
Pigt 2 1746 4 4 8
Pigu 2 1305 10 3 13
Dpm3 3 276 0 1 1
Pigk 3 1185 7 1 8
Pigo 4 3303 5 4 9
Pigv 4 1479 5† 6 11
Pigg 5 2925 NA* NA* NA*
Pgap2 7 750 1 3 4
Pigb 9 1626 7 3 10
Pigy 9 213 0 0 0
Mpdu1 11 741 0 0 0
Pigl 11 756 3 1 4
Pigs 11 1665 3 0 3
Pigw 11 1509 1 1 2
Pigh 12 564 1 0 1
Gpaa1 15 1863 6 1 7
Pigp 16 396 1 1 2
Pigx 16 756 6 3 9
Pigf 17 657 2 2 4
Pigq 17 1743 NA* NA* NA*
Piga X 1455 NA* NA* NA*
   (Total) 71 44 115
  1. *Four genes excluded from screening targets (see text).
  2. †One H129-2 clone has two mutant alleles (see Table 2 and Figure 2).