Figure 5

Significance of p63 motif. The genomic coordinates of all the accessible locations in human keratinocytes, as determined by DNase-Seq in NHEK cell-line, were obtained from ENCODE via the UCSC genome browser. The 145,203 accessible locations are divided into 3 groups 1) 4153 locations with strong p63 motif (motif score >7.14), 2) 10,503 locations with weak motif (7.14 > motif score >2.24) and 3) 130547 locations with no motif. Box and Whisker Plots are made across 500 bp window for (A) Experimental p63 occupancy, (B) Predicted p63 occupancy by our best 3 regression model, (C) DNase tag density, (D) H3K4me1 tag density.