Transcriptome structure variability in Saccharomyces cerevisiae strains determined with a newly developed assembly software

Table 2 Selected results obtained from GO analysis

GO category	Characteristics of the category	Genes	p-value
GO:0006790 - Sulfur compound metabolic process	Variable 5’-UTR in S. cerevisiae strains	CYS3, MIS1, PHO3, THI2, MET6, YHR112C, BAT1, MET1, IRC7, GLO2, THI4, TRX2, YLL058W, GTT2, SAM1, GSH2, THI20, THI80, GLR1, THI6, MRI1, THI22	1.5*10⁻⁵ (6 g/l)
GO:0000947 - Amino acid catabolic process to alcohol via Ehrlich pathway	Variable 5’-UTR in S. cerevisiae strains	SFA1, ADH4, PDC5, ADH3, ADH1	6.4*10⁻⁴ (6 g/l)
GO:0016125 - Sterol metabolic process	Highly conserved 5’-UTR in S. cerevisiae strains	ERG28, NCP1, NSG1, UPC2, ERG26, ERG4, ERG20, HMG2, ERG5, ERG12, ERG8, MVD1, HES1, ERG10, DAP1	6.1*10⁻⁶ (6 g/l)
GO:0016125 - Sterol metabolic process	Variable 5’-UTR in S. cerevisiae strains	RSP5, ERG11, ERG7, ERG9, ERG25, ERG3, ERG27, ERG6, ERG2, CYB5, ERG24, IDI1, KES1	1.1*10⁻³ (6 g/l)
GO:0055085 - Transmembrane transport	Conserved SAUT among strains at 6 g/l	SUL1, YHK8, PDR11, VCX1, AZR1, PEX21, YMR279C, YNL095C, FRE7, CTR1	0.0052 (6 g/l)
GO:0031505 - Fungal-type cell wall organization	Conserved SAUT among S. cerevisiae strains at 45 g/l	TIP1, UTR2, SIM1, TAX4, SPO75, YLR194C, WSC2, HPF1	0.0059 (45 g/l)
GO:0006820 - Anion transport	Conserved SAUT among S. cerevisiae strains at 45 g/l	BAP2, SUL1, FAT3, FET3, YMR279C, ATO2, FAA1	0.019 (45 g/l)
GO:0022413 - Reproductive process in single cell organisms	Conserved SAUTs among sensu stricto yeast species	RRT12, SPO77, SMA2, PRM1	1.66*10⁻³

Relevant results obtained from analysis of the enrichment of genes involved in selected GO processes. Enrichment was calculated with respect to the entire set of S. cerevisiae genes using YeastMine and the p-value is reported on the rightmost column (http://yeastmine.yeastgenome.org/yeastmine/begin.do).

ISSN: 1471-2164