Figure 1

A schematic view of our hypothesis. If the binding peak is shorter than 3,000 bp, we equally extended from the two ends to have a length up to 3,000 bp. We assume that in addition to the CREs of the ChIP-ed TF (red circle), CREs of different cooperative TFs (the other shapes) are also enriched in the neighborhoods of at least some subsets of the binding peak dataset. Each line represents an extended binding peak sequence.