Table 5 Genomic changes between strains P5 and P24 in the genes of the sulfur assimilation pathway and glutathione biosynthesis

MET4

Gln⁶²⁹-His

Regulation of sulfur metabolism

MET28

Lys⁹²-Glu

Regulation of sulfur metabolism

MET1

Gly⁵⁷⁸-Asp

Sulfate assimilation and methionine biosynthesis

GTT1

Gly²³¹-Asp

Glutathione metabolic process

SUL1

Ala⁹⁹-Val

Sulfur assimilation

HYR1

Lys¹⁷²-Glu

Cellular response to oxidative stress

GTO2

Trp¹⁷²-Leu

Glutathione metabolic process

SUL2

Ala⁸⁰⁹-Ser

Sulfur assimilation

ECM5

Asn⁵⁰⁴-Lys

Cellular response to oxidative stress

SAM3

Glu⁵⁷⁰-Lys

S-adenosyl-L-methionine transport

SSE1

Asp⁶⁹¹-Gly

ATPase component of the heat shock protein Hsp90 chaperone complex

SSU1

Met¹⁹-Val

Sulfite transport

CYS4

Ser⁵⁰⁴-Asn

Cysteine biosynthesis

GSH1

Ser⁴⁹⁶-Arg

Glutathione biosynthetic process

STR2

Gln⁴⁰³-Lys

Cystathionine biosynthesis