RNA-seq and high-definition mass spectrometry reveal the complex and divergent venoms of two rear-fanged colubrid snakes

Table 7 HyPhy [68] selection analysis using the SLAC, FEL, and REL methods

		Subst.	Total	SLAC codons	FEL codons	REL codons
Toxins	n	model	codons	w>1; P<0 .05	w>1; P<0 .05	w>1; B F>100
SVMP-MP	18	REV	192	1	11	7
SVMP-DIS	17	HYK85	76	2	5	10
SVMP-ACR	17	HKY85	102	1	5	16
3FTx	11	REV	79	0	1	35
CTL	12	REV	137	0	2	0
Ficolin	7	REV	324	0	0	4

Abbreviations: SLAC–single-likelihood ancestor counting, FEL–fixed-effects likelihood, REL–random-effects likelihood, SVMP–snake venom metalloproteinase, MP–metalloproteinase domain, DIS–disintegrin domain, ACR–cysteine-rich domain, 3FTx–three-finger toxin, CTL–C-type lectin, w–ratio of nonsynonyous to synonymous substitution rates, n–number of sequences (duplicates removed), BF–Bayes factor.

ISSN: 1471-2164