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Table 1 Proteins identified as differentially-expressed following exposure to nitrosative stress

From: Label-free proteomic analysis to confirm the predicted proteome of Corynebacterium pseudotuberculosis under nitrosative stress mediated by nitric oxide

Uniprot access Proteins Score Peptides log2DETA:CT(a) p-value(a) Subcellular localization(c) Gene name Genome(b)
Transport         
F9Y2Z3_CORP1 Cell wall channel 5321.88 4 1.42 1 CYT porH Shared
Cell division         
D9Q7G2_CORP1 Hypothetical protein 2417.8 21 1.34 1 CYT Cp1002_0716 Core
DNA synthesis and repair         
D9Q5V6_CORP1 Nucleoid-associated protein 2327.08 5 1.52 1 CYT ybaB Core
D9Q923_CORP1 Methylated-DNA-protein-cysteine methyltransferase 6332.83 8 1.22 1 CYT ada Core
D9Q4P0_CORP1 7,8-dihydro-8-oxoguanine-triphosphatase 1640.23 8 -1.97 0 CYT mutT Core
Transcription         
D9Q8W2_CORP1 LexA repressor 800.31 6 -1.37 0.04 CYT lexA Shared
D9Q5L4_CORP1 ECF family sigma factor k 364.82 8 -1.58 0 CYT sigK Core
Translation         
D9Q753_CORP1 Fkbp-type peptidyl-prolyl cis-trans isomerase 7113.34 3 2.43 1 CYT fkbP Core
D9Q830_CORP1 50S ribosomal protein L35 2271.66 1 1.36 1 CYT rpmI Core
D9Q7W1_CORP1 Aspartyl glutamyl-tRNA amidotransferase subunit C 3100.8 7 1.24 0.99 CYT gatC Core
D9Q582_CORP1 50S ribosomal protein L9 41082.46 10 -1.25 0 CYT rplI  
D9Q6H6_CORP1 30S ribosomal protein S8 45333.23 9 -1.34 0 CYT rpsH Core
Cell communication         
D9Q559_CORP1 Hypothetical protein 1402.27 6 1.99 1 PSE Cp1002_2005 Core
D9Q5U9_CORP1 Thermosensitive gluconokinase 2068.35 7 1.96 0.99 CYT gntK Core
D9Q668_CORP1 Sensory transduction protein RegX3 2540.92 13 1.45 1 CYT regX3 Core
Detoxification         
D9Q7U6_CORP1 Thioredoxin 1835.7 11 1.50 1 CYT trxA Core
D9Q4E5_CORP1 Glutathione peroxidase 1426.27 10 1.47 1 CYT Cp1002_1731 Core
D9Q5T5_CORP1 Glyoxalase bleomycin resistance protein dihydroxybiphenyl dioxygenase 2417.77 11 1.28 1 CYT Cp1002_0124 Shared
D9Q5N2_CORP1 NADH dehydrogenase 7030.94 12 1.25 1 CYT noxC Shared
D9Q680_CORP1 Glutaredoxin-like domain protein 292.69 2 -1.91 0 CYT Cp1002_0272 Core
Glycolysis pathways         
D9Q5B6_CORP1 N-Acetylglucosamine kinase 228.69 6 1.74 0.98 CYT nanK Core
D9Q4U9_CORP1 Alcohol dehydrogenase 236.02 17 1.22 1 CYT adhA Shared
Iron-sulfur clusters         
D9Q7L6_CORP1 Ferredoxin 36927.57 7 2.10 1 CYT fdxA Core
Antibiotic resistance         
D9Q827_CORP1 Metallo-beta-lactamase superfamily protein 657.33 6 -2.95 0 CYT Cp1002_0937 Core
Amino acid metabolism         
D9Q622_CORP1 Phosphoserine phosphatase 949.15 9 1.58 0.99 PSE serB Core
D9Q4N1_CORP1 Carboxylate-amine ligase 205.54 16 1.24 1 CYT Cp1002_1819 Core
D9Q6H4_CORP1 L-serine dehydratase I 284.11 17 -1.37 0 MEM sdaA Core
Lipid metabolism         
D9Q520_CORP1 Glycerophosphoryl diester phosphodiesterase 2417.8 21 1.34 1 PSE glpQ Core
Oxidative phosphorylation         
D9Q8I5_CORP1 Cytochrome aa3 controlling protein 676.2 6 1.28 1 MEM Cp1002_1095 Core
Specific metabolic pathways         
D9Q5M9_CORP1 Inositol-3-phosphate synthase 7473.38 18 2.25 1 CYT ino1 Core
D9Q721_CORP1 Hypothetical protein 4602.9 17 1.44 1 SEC Cp1002_0573 Core
D9Q689_CORP1 3-Hydroxyisobutyrate dehydrogenase 2137.24 12 1.34 1 CYT mmsB Core
D9Q4X1_CORP1 Urease accessory protein UreG 1532.39 12 -1.6 0 CYT ureG Core
Nucleotide metabolism         
D9Q4S2_CORP1 Orotate phosphoribosyltransferase 2618.52 8 -1.26 0 CYT pyrE Core
Unknown function         
D9Q6Y9_CORP1 Hypothetical protein 491.89 10 2.87 1 CYT Cp1002_0540 Core
D9Q6C7_CORP1 Hypothetical protein 689.6 25 2.25 1 PSE Cp1002_0320 Core
D9Q3P3_CORP1 Hypothetical protein 5703.38 3 1.87 1 CYT Cp1002_1474 Core
D9Q5V4_CORP1 Hypothetical protein 994.52 1 1.7 1 CYT Cp1002_0143 Core
D9Q610_CORP1 Hypothetical protein 27217.36 2 1.67 1 CYT Cp1002_0202 Core
D9Q8D8_CORP1 Hypothetical protein 2324.12 7 1.57 0.98 CYT Cp1002_1048 Shared
D9Q6W1_CORP1 Hypothetical protein 9303.91 4 1.54 1 CYT Cp1002_0512 Core
D9Q6V5_CORP1 Hypothetical protein 1346.2 4 1.5 0.99 CYT Cp1002_0506 Core
D9Q5R7_CORP1 Hypothetical protein 2090.7 8 1.42 1 CYT Cp1002_0105 Core
D9Q917_CORP1 Hypothetical protein 555.89 10 1.37 1 PSE Cp1002_1281 Core
D9Q3P5_CORP1 Hypothetical protein 1121.7 6 1.29 1 SEC Cp1002_1476 Core
D9Q7U5_CORP1 Hypothetical protein 517.06 8 1.28 1 CYT Cp1002_0852 Core
D9Q7L1_CORP1 Hypothetical protein 15693.97 6 1.28 1 SEC Cp1002_0766 Core
D9Q3P6_CORP1 Hypothetical protein 1729.59 5 1.22 1 CYT Cp1002_1477 Core
D9Q6Z7_CORP1 Hypothetical protein 1835.7 13 1.22 1 CYT Cp1002_0548 Core
D9Q8V8_CORP1 Hypothetical protein 293.23 8 -1.48 0   Cp1002_1221 Core
D9Q6C8_CORP1 Hypothetical protein 413.31 12 -1.52 0 PSE Cp1002_0321 Core
D9Q5H0_CORP1 Hypothetical protein 12376.2 6 -1.71 0 CYT Cp1002_0007 Core
D9Q4D5_CORP1 Hypothetical protein 10161.64 4 -4.29 0 CYT Cp1002_1721 Shared
Others         
D9Q5N5_CORP1 Iron-regulated MEM protein 992.54 8 2.01 0 PSE piuB Core
D9Q922_CORP1 CobW/HypB/UreG, nucleotide-binding 1771.22 20 1.88 1 CYT Cp1002_1286 Core
D9Q8C4_CORP1 Prokaryotic ubiquitin-like protein Pup 2194.86 1 1.84 1 CYT pup Core
D9Q7B8_CORP1 Ribosomal-protein-alanine n-acetyltransferase 2791.1 10 1.34 1 CYT rimJ Shared
D9Q7K9_CORP1 Arsenate reductase 5147.54 8 1.32 1 CYT arsC Core
  1. (a) Ratio values to: strain 1002_DETA/NO:strain 1002_Ct, Log(2) Ratio > 1.5, p > 0.95 = up-regulation, p < 0.05 = down-regulation.
  2. (b) Core-genome analysis of 15 strains of C. pseudotuberculosis: shared = present in two or more strains; core = present in 15 strains of C. pseudotuberculosis.
  3. (c) CYT =cytoplasmic, MEM = membrane, PSE = potentially surface-exposed, SEC = secreted.