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Figure 3 | BMC Genomics

Figure 3

From: Novel and unique domains in aminoacyl-tRNA synthetases from human fungal pathogens Aspergillus niger, Candida albicans and Cryptococcus neoformans

Figure 3

Comparison of domain architectures of A. niger and H. sapiens aaRSs. Homologous proteins from C. albicans and C. neoformans are also shown. (A) An uncharacterized protein family (UPF) domain at the N-terminal of A. niger IleRS (212883-mRNA) is absent in the homolog from H. sapiens. A. niger and H. sapiens IleRSs share ~36% sequence identity. (B) Comparison of domain architectures of ValRS from A. niger (194077-mRNA) and H. sapiens. Brix domain at the C-terminal is unique to A. niger ValRS, and these two ValRSs are ~46% identical. (C) A. niger AsxRS has a unique domain of unknown function (DUF) C-terminal to the catalytic domain. A. niger AsxRS and H. sapiens AspRS are ~45% identical.

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BMC Genomics

ISSN: 1471-2164

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