Comparative genomics of Lactobacillus crispatus suggests novel mechanisms for the competitive exclusion of Gardnerella vaginalis

Table 4 Distribution of predicted bacteriocin related proteins in L. crispatus

Bacteriocin class	Bacteriocin type	PFAM	125-2-CHN	214-1	CTV-05	FB049-03	FB077-07	JV-V01	MV-1A-US	MV-3A-US	SJ-3C-US	ST1	Total	Total with domain
Bacteriocins larger than 10kD, Class III	Enterolysin A	Peptidase_M23	1/1	2/2	2/2	2/2	2/2	2/2	2/2	2/2	2/2	2/2	10	10
	Bacteriocin helveticin J	-	1	1	1	1	1	1	1	1	1	1	10	-
	Helveticin J	-	1	1	1	1	2	1	1	1	1	1	10	-
LAPs	Small orfs	-	1	0	0	1	1	0	1	0	0	0	4	-
Small unmodified bacteriocins, Class II	Penocin A	Bacteriocin_II	1/2	0	1/2	1/2	1/2	0	0	1/2	1/1	0	6	6
Small unmodified bacteriocins, Class II	LS2, chain A	Bacteriocin_IIc	1/1	1/1	1/1	1/1	1/1	1/1	1/1	1/1	1/1	0	9	9
		Total	7	5	7	8	9	5	6	7	6	4	49	25

For the bacteriocin-like molecules with PFAM-domain, the first number in the table cells describes the number of CDSs part of the ortholog group in a specific strain, and the second number indicates the number of group members having the PFAM-domain. Helveticin J refers to the antimicrobial molecule first identified in L. helveticus and bacteriocin helveticin J to one identified in L. acidophilus.

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