Overview of correlation between of the genes involved in thiamine biosynthesis and utilization. (A) Example of correlated expression level: PDC1 vs THI11 (negative correlation), AAD14 vs THI11 and PDC1 vs R70. Expression level corresponds to array log2(I). Parental strains are indicated with triangles. (B) Principal component analysis using as variables the fermentation rate (R70) and expression levels of several genes involved in thiamine biosynthesis and utilization. The first diagonal corresponds to fermentation rate parameters. The second diagonal corresponds to THI3 origin.