Comparison of results generated by using Categorizer and a GO-Slim-based approach. A. Overall accuracies of Categorizer, GO Slim and a random predictor. The categories of genetic modifiers obtained from a high-throughput screening study (Zhang et al.) were used as a gold standard. B. Enrichment of the 9 categories. All the genes tested for HD were used as a reference. C. Numbers of genes for each category in the test and randomized reference sets. Since we allowed multiple categorization, one gene may appear in several categories. Significantly enriched categories (p < 10-2) were marked as *.