Table 1 PBNT embryo development after VPA treatment

VPA at different concentrations (mM)

Control

136

98(72.1)^a

69(50.7)^a

2(1.5)

2(1.5)

0.5

153

120(78.4)^a

95(61.9)^a

2(1.3)

1(0.7)

1.0

147

104(70.7)^a

75(51.0)^a

1(0.7)

1(0.7)

2.0

138

81 (58.7)^b

29(21.0)^b

1(0.7)

0(0.0)

4.0

158

79(50.0)^b

12(7.6)^b

0(0.0)

0(0.0)

VPA at 0.5 mM for differenttimes (h)

Control

118

83(70.3)^a

52(44.1)^b

1(0.8)

1(0.8)

5

142

99 (69.7)^a

60(42.3)^b

1(0.7)

1(0.7)

12

151

107(70.9)^a

71(47.0)^b

1(0.7)

1(0.7)

24

146

111(76.0)^a

95(65.1)^a

1(0.7)

1(0.7)

48

149

102(68.5)^a

74(49.7)^b

0(0.0)

0(0.0)